The goal of neurodynamic stretching is to stretch & stimulate nerve tissue specifically — not muscles.
Neurodynamic stretching is a technical type of stretching, usually provided by a professional, designed to treat neuropathy by stretching nerves. It is a bit obscure, and the science is thin, but it’s an interesting idea that’s been around for a long time. It may also partly explain why common, simple stretching feels so darn good.
Some pain is caused by physical interference with nerves — neuropathies like carpal tunnel syndrome or sciatica.1 Neural mobilization or neurodynamics is a loose collection of experimental stretching and positioning treatments for neuropathy based on the idea that “unhappy” nerve tissue can be helped with the stimulation of stretch.
But not just any movement! Only quite specific movements need apply. If you really know your stuff, you can move in a way that emphasizes effects on nerves rather than muscles and tendons. “Stretching” isn’t really a good term, an oversimplification to get us started without too much jargon. More specifically, it may be possible to slide nerves in their sheathes (neural gliding or sliding or, the goofiest term, neural flossing)… or just pulling on the whole thing (neural tensioning). Some of the movements superficially look like conventional stretching, but neural sliding and tensioning are also possible without anything that looks like stretching at all.
Overlap with stretching
To the extent that neurodynamics can involve some stretch-like movements — some versions are “stretchier” than others — it is good example of a specialized type of stretching that might have genuine benefits for some patients. Indeed, perhaps more than stretching in general, which is not only hugely overrated as a therapeutic tool or pillar of fitness,2 but also conspicuously lacking in supposedly “advanced” methods that are proven to be superior to just doing whatever feels nice.
If neurodynamics is effective, it would be an impressive partial vindication of therapeutic stretching. Spoiler alert: no one actually knows if it works, because…
Neurodynamics: barely studied
There is plenty of science that’s relevant to the underlying principles, but not clinical trials of its application. Nerves have been studied plenty, but not the efficacy of nerve stretching as a treatment.
Neural mobilization is a tough thing to test — technical, hard to standardize, rotten with confounding factors. The science is so threadbare that I’m going to skip citations other than a single review.3 Writing my own informal literature review would just be frustrating and disappointing for everyone, a doomed attempt to pull a useful signal out of a little bit of noise (an annoyingly common problem at the fringes of musculoskeletal medicine, which is surprisingly primitive in general4).
So neurodynamics is not a scientifically validated therapy. But it hasn’t actually been kicked to the curb yet either. It remains plausible and interesting, and no advanced discussion of stretching for pain would be complete without it.
Meet the wire-pipes
“Wiring” seems like the obvious metaphor for nerves, but “plumbing” is surprisingly apt as well. Nerves may not be as much like pipes as blood vessels, but they are actually more like pipes than wires when it comes to how they work. They are like fancy plumbing doing an impressive imitation of an electrical system.
All nerves are tubes filled with fluid. Although the fluid doesn’t flow, it is wet, which is necessary for all the messy chemistry that allows nerves to play with electricity (just like in batteries). Their clever simulation of a flowing “current” is achieved by ions zipping back and forth across the membrane (action potentials), not by flowing along the length of the nerve (think of a stadium “wave”).
No pipe or wire works like that, of course. These physiology metaphors always fall apart when you start looking too closely.
The chemistry of nerve impulses is sensitive to any interference with the integrity of that membrane. Wires can be kinked like a garden hose with no loss of functionality, but not nerves. Inflammation and other biochemical sources can also mess with nerve function (e.g. several poisons).
Many causes of neuropathy are simple, just straight up pinching. But there are more subtle paths to neuropathy — like not gliding smoothly in their sheaths. Most nerves have a wrapping, but it doesn’t function like the insulation on a wire. Nerves need their own specialized fluid environment for optimal function, so they are a fluid-fluid tube inside another fluid-filled tube. Nested pipes! Exactly like the way the brain and spinal cord are also packed in fluid, just smaller. The whole nervous system is packed in fluid like this, from nerves as thick as your thumb to nerves so tiny they make hairs look like tree trunks.
They are all packed in fluid, and they are all free to slide in those fluid-filled channels to some degree.
Unless they aren’t.
Larger peripheral nerves consist of bundles of nerve fibres, bundled into larger bundles along with blood vessels — nested “pipes.”
Tunnel syndromes and neural tension: the consequences of nerve snags (from the reasonably certain to the highly speculative)
Sometimes, due to pathological processes and physical predicaments, nerves get pressed against and stuck to the walls of their tubes, like microscopic velcro. This predicament is usually called “neural tension” or a “tunnel syndrome.” You don’t want this happening to your nerves any more than your cat wants tape on its paws. It affects their function.5
There are several infamous and obvious “tunnel syndromes,” most notably carpal tunnel syndrome.6 A more obscure example — yet still fairly common — is Baxter’s neuritis, or tarsal tunnel syndrome.
Subtler tunnel syndromes
For every pathologically blatant tunnel syndrome, there could be many subtler ones, and these might cause a lot of milder neuropathy. This is unconfirmed, but not especially controversial. This scenario is usually called “neural tension” rather than a “tunnel syndrome.”
But what if we ventured even further out onto this limb? What if the most subtle neural stuckness can cause symptoms that would never actually be diagnosed as neuropathy? Just vague aches and twinges and discomfort? Some experts have proposed that these little micro nerve entrapments are actually the specific cause of the “trigger point” phenomenon — humanity’s plague of unexplained sore spots.7
An interesting hypothesis, but that’s all it is so far. It’s completely unclear whether these subtler scenarios happen at all, or to what degree, or whether it is possible to treat them.
Free the nerves! One goal of neural mobilization is to break adhesions
“It’s trapped, I say! Trapped!”
You may have guessed it from the setup: one major goal of neural gliding is to free the nerves, by stretching in such a way that they actually pull free of their putative adhesions and entrapments. This sounds traumatic, but it could be so microscopic that we don’t feel a thing as it happens, or only the normal discomfort of a strong stretch.
Anything that feels like a stretch is undoubtedly causing many, many nerves to slide in their sheaths to some degree, and maybe this is a reason why stretch feels good/healthy: because it breaks up lots of little neural adhesions. Which may or may not exist. And probably not much more than miscellaneous physical activity, and maybe not all, but still, it might be why people like stretching. Just keeping those wire-pipes slip-sliding around nicely!
Neural gliding as a formal therapeutic method is more focused: specific stretches based on detailed anatomical knowledge required to apply maximal tension to specific nerves. There are professionals who have devoted a great deal of energy to learning how to tug on many different nerves.
Heck of a thing, really. Imagine pursuing so much specialized knowledge about a largely unvalidated approach to solving a problem that may or may not exist. Welcome to musculoskeletal medicine!
A humbler goal: maybe it’s just nerve exercise?
Neural gliding often has the goal of breaking adhesions between nerves and their sheathes, but not everyone thinks that’s the point. In contrast, a simpler goal of neural tensioning is just to pull on nerves, without optimizing for “glide” of the nerve within a sheath to break adhesions. That is, some stretches pull on both sheath and nerve more equally.
I am not aware of any specific rationale for this, other than the basic idea that it’s basically just a way of stimulating/exercising them, which is in turn is widely regarded a Good Thing. And maybe it’s good enough. Indeed, some professionals think that’s the only defensible goal of any kind of nerve stretching. Not everyone agrees that the purpose of neurodynamic stretching is to rip free nerves from possibly imaginary adhesions or entrapments (which might not be clinically significant even if they do exist).
Pretty much everything in physiology seems to thrive on just-right levels of stimulation. “Motion is lotion” and “exercise is the closest thing we have to a miracle cure” and so on. Tissue stagnancy might drive dysfunction and neuropathy — essentially an exaggeration of feeling increasingly uncomfortable if we are too still for too long.
This justification for nerve stretching is probably on firmer ground than “it’s about entrapment,” but it’s still far from a slam dunk. I don’t think anyone doubts that stimulation is good for nerves in some sense, but … do we have to specifically stretch nerves to achieve it? Is it clinically important to do so?
It could be. Not everything in biology functions or heals well solely with the stimulation of normal activity!8
On the other hand, a great many medical interventions and “crutches” that supposedly facilitate healing have turned out to be surprisingly useless or even harmful.9 What actually assists the body is not obvious. Rigorous study is the only way we’re ever really going to know if specifically stretching nerves is helpful — as opposed to, say, something else specific like stretching blood vessels, or something general like just doing some calisthenics.
The rigorous study has not been done, of course. Until it is done, the value of nerve stretching cannot possibly be anything better than an educated guess.
Nerve tension and stretch tolerance
Hitting the natural and pathological limits of how far nerves can be pulled is one of the things that determines how intense a stretch feels. We may think we’ve stretched as far as we can not because we’ve hit the mechanical limit of the extensibility of our tissues, but because we’ve moved a nerve as far as it can be moved in its sheath. Nerve stretch may be what causes discomfort when you’re deep in a hard stretch, and it might be why some stretches are more unpleasant to hold than others.
This is particularly important because our “tolerance” for stretch is probably the main thing that changes when we increase our flexibility — not the actual physical properties of our tissues. I explore this concept in great detail in my stretching article.
About Paul Ingraham
I am a science writer in Vancouver, Canada. I was a Registered Massage Therapist for a decade and the assistant editor of ScienceBasedMedicine.org for several years. I’ve had many injuries as a runner and ultimate player, and I’ve been a chronic pain patient myself since 2015. Full bio. See you on Facebook or Twitter, or subscribe:
What’s new in this article?
Although first published as an independent article on Jun 8, 2021, the content was originally created a bit earlier as a chapter for my stretching article on April 25. I decided it warranted a page of its own.
Feb 24, 2022 — New section: “A humbler goal: maybe it’s just nerve exercise?”
2021 — Miscellaneous editing and revision after publication as an independent article. Added artwork and pull quotes.
2021 — Publication.
- Well-known neuropathies include sciatica, carpal tunnel syndrome, and shingles. Banging your “funny bone” (the ulnar nerve) is technically a brief, trivial neuropathy. In musculoskeletal medicine (the focus of PainScience.com), we are mostly concerned with relatively simple neuropathies caused by impingement and trauma, and not so much by disease… but not necessarily. Pain is complex, and sometimes it is caused by neuropathy with a complex pathological backstory.
- Stretching is not a pillar of fitness: it doesn’t warm you up, prevent or treat soreness or injury, or enhance peformance, but it can cause injuries and (slightly) impair performance. It’s possible to increase flexibility, but the value of flexibility is surprisingy low, even for most athletes. Many key muscles are mechanically impossible to stretch in the first place. Stretch might help some kinds of pain, like muscle pain, but that’s quite speculative. There is no “advanced” stretching method that overcomes any of these limitations. See Quite a Stretch: Stretching science has shown that this extremely popular form of exercise has almost no measurable benefits.
- Basson A, Olivier B, Ellis R, et al. The Effectiveness of Neural Mobilization for Neuro-Musculoskeletal Conditions: A Systematic Review and Meta-Analysis. J Orthop Sports Phys Ther. 2017 Jul:1–76. PubMed #28704626 ❐
The level of evidence for neural mobilization is “largely unknown” according to this review of forty studies (only seventeen with a low risk of bias, and with lots of variety in methods throughout). The results were mixed, and NM notably failed for relatively straightforward peripheral neuropathies like carpal tunnel syndrome — if NM is good for anything, it should be good for that, at least.
On the bright side, according to the paper, the data “reveals benefits of NM for back and neck pain,” but these are complex conditions and notoriously multifactorial, so I remain pessimistic in the absence of more and better data. As the authors understate: “Due to the limited evidence and varying methodological quality, conclusions may change over time.” I’d say it’s so likely that “conclusions may change” that the word “conclusion” isn’t really useful here.
- We can put a man on the moon, but we can’t treat chronic pain. The science and treatment of pain and injury was neglected for decades while medicine had bigger fish to fry, and it remains a backwater to this day. The seemingly simpler “mechanical” problems of injury and rehab have proven to be surprisingly weird and messy. Oversimplification and quackery still dominate the field. For more information, see A Historical Perspective On Aches ‘n’ Pains: We are living in a golden age of pain science and musculoskeletal medicine … sorta.
- The membrane of the nerve itself is no longer floating freely, so ions can no longer rush in and out of that section of membrane quite so well. The result: pain, numbness, tingling.
- The tunnel term mainly refers to glaring cases of nerves that have gotten pinched in some of the larger, more obvious nerve sheathes, like the carpal tunnel. The tunnel can get narrowed by various mechanisms, like swelling, and adhesions may also form (basically getting pinched and then also stuck).
- Quintner JL, Bove GM, Cohen ML. A critical evaluation of the trigger point phenomenon. Rheumatology (Oxford). 2015 Mar;54(3):392–9. PubMed #25477053 ❐ Quintner et al. have hypothesized that “irritated peripheral nerve trunks” are “a rich source” of pain, and may be the true cause of trigger points, rather than the more conventional idea that they are “micro cramps.”
- A simple example: deliberately washing wounds is dramatically better at preventing infection than just letting nature take its course. Simple mechanical flushing can be extremely powerful.
- Orthopedic surgery is one of the most relevant and obvious categories, and in that category nothing is more startlingly counterintuitive than the example of unnecessary tendon repair. It seems like ruptured tendons cannot possibly heal without being surgically anchored. But biology was healing tendon ruptures long before surgeons came along! Achilles tendon re-rupture is only slightly less likely with surgery… and with more complications (Ochen).