Five articles on PainSci cite Rathbone 2017: 1. Does Massage Therapy Work? 2. The Complete Guide to Trigger Points & Myofascial Pain 3. The Complete Guide to Low Back Pain 4. Is Diagnosis for Pain Problems Reliable? 5. Trigger Point Doubts
PainSci commentary on Rathbone 2017: ?This page is one of thousands in the PainScience.com bibliography. It is not a general article: it is focused on a single scientific paper, and it may provide only just enough context for the summary to make sense. Links to other papers and more general information are provided wherever possible.
This is a meta-analysis of 6 studies of how much different experts can agree on the location of myofascial trigger points (inter-rater reliability). They had to “estimate” an agreement score of 𝛋=0.452 — a rather precise estimate! Of the criteria used to determine the location of trigger points, the most reliable were localized tenderness (.68) and pain recognition (.57).
Those are actually not terrible reliability scores. Obviously they could be better, and it would be nice if they were, but it’s important context that most attempts to detect pathologies in the body are technically “unreliable,” falling well short of a score of κ=1.0 (perfect agreement), but still much better than κ=0 (coin flipping agreement).
And the error bars on those estimates were too large for a confident conclusion anyway.
Therefore, my conclusion is that this review was mostly inconclusive, but actually found evidence that trigger point reliability is probably not all that bad (compared to what you’d expect from a diagnostic procedure for something that doesn’t actually exist).
~ Paul Ingraham
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
OBJECTIVE: To achieve a statistical estimate of the agreement of manual palpation for identification of myofascial trigger points (MTrPs) and secondarily to investigate potential factors impacting the agreement of this technique.
METHODS: We searched MEDLINE(R) and Embase for studies examining the reproducibility of manual palpation for the identification of MTrPs from the year 2007 to present. In addition, we utilized studies identified by 2 comprehensive systematic reviews that covered the period before 2007. The included studies were original peer-reviewed research articles and included Cohen κ measures or data with which to calculate Cohen κ. Studies were excluded if they lacked a measure of variability or information required to calculate variability. Studies that examined palpation through body cavities were also excluded. Of the 18 potentially relevant articles only 6 met inclusion criteria including 363 patients. Modified QUADAS tool was used to assess study validity. Subgroup comparisons were made utilizing Q and Z tests.
RESULTS: An estimate of κ=0.452 (95% confidence interval, 0.364-0.540) was obtained for interrater agreement of manual palpation of MTrPs. Localized tenderness (κ=0.676) and pain recognition (κ=0.575) were the most reliable criteria. Only 1 study met inclusion criteria for intrarater agreement and therefore no meta-analysis was performed.
DISCUSSION: Use of manual palpation for identification of MTrPs is unreliable, and future investigation should focus on integration with more reliable techniques.
- “Reliability of physical examination for diagnosis of myofascial trigger points: a systematic review of the literature,” Nicholas Lucas, Petra Macaskill, Les Irwig, Robert Moran, and Nikolai Bogduk, Clinical Journal of Pain, 2009.
- “A systematic, critical review of manual palpation for identifying myofascial trigger points: evidence and clinical significance,” Corrie Myburgh, Anders Holsgaard Larsen, and Jan Hartvigsen, Archives of Physical Medicine & Rehabilitation, 2008.
- “Clinical precision of myofascial trigger point location in the trapezius muscle,” V M Sciotti, V L Mittak, L DiMarco, L M Ford, J Plezbert, E Santipadri, J Wigglesworth, and K Ball, Pain, 2001.
- “Interrater reliability in myofascial trigger point examination,” R D Gerwin, S Shannon, C Z Hong, D Hubbard, and R Gevirtz, Pain, 1997.
- “Travell, Simons and Cargo Cult Science,” Fred Wolfe, FMperplex.com.
- “The fibromyalgia and myofascial pain syndromes: a preliminary study of tender points and trigger points in persons with fibromyalgia, myofascial pain syndrome and no disease,” F Wolfe, D G Simons, J Fricton, R M Bennett, D L Goldenberg, R Gerwin, D Hathaway, G A McCain, I J Russell, and H O Sanders, Journal of Rheumatology, 1992.
- “Interrater reliability: the kappa statistic,” Mary L McHugh, Biochem Med (Zagreb), 2012.
- “The measurement of observer agreement for categorical data,” J R Landis and G G Koch, Biometrics, 1977.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- No long-term effects after a three-week open-label placebo treatment for chronic low back pain: a three-year follow-up of a randomized controlled trial. Kleine-Borgmann 2022 Pain.
- Exercise and education versus saline injections for knee osteoarthritis: a randomised controlled equivalence trial. Bandak 2022 Ann Rheum Dis.
- Association of Lumbar MRI Findings with Current and Future Back Pain in a Population-based Cohort Study. Kasch 2022 Spine (Phila Pa 1976).
- A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Yousef 2013 Anaesthesia.
- Is Neck Posture Subgroup in Late Adolescence a Risk Factor for Persistent Neck Pain in Young Adults? A Prospective Study. Richards 2021 Phys Ther.