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What toxins actually are

Paul Ingraham ARCHIVEDMicroblog posts are archived and rarely updated. In contrast, most long-form articles on are updated regularly over the years (see updates page).

The idea of “toxins” is usually used as a tactic to scare people into buying de-toxifying snake oil of one sort or another. What is meant by it? The folks who sell detoxification are notoriously vague.

I delved into this while writing an update for my Epsom salts article recently, and it ended up being quite useful in a couple other articles too: my main toxins page (duh), of course, and my article picking apart the popular practice of promoting hydration after massage.

A poison is literally any harmful substance, and even something safe in typical doses becomes a poison in overdose (so you can be poisoned by either lots of water or a minuscule amount of lead). Toxins are technically poisons produced by living things, like venom or metabolic wastes, but informally the word is synonymous with poison.

There’s a staggering variety of poisons/toxins, but the two major categories that are probably what most regular people hope they can purge are pollutants and metabolic “wastes”:

Pollutants are probably what most regular people hope they can get rid of with a detox. The best specific candidates would be the persistent organic pollutants like pesticides, flame retardants, and polychlorinated biphenyls (PCBs, now banned, but formerly ubiquitous in many plastics). Lead is also an alarmingly common environmental poison (and much in the news lately). All of these are indeed found in our environment and our bodies, where they mostly get trapped in fat and otherwise sequestered. We definitely would like to get rid these … if only we could.

Metabolic “wastes” is a much murkier category, because many of them aren’t “wastes” at all. Cellular chemistry produces a lot of molecules, with many fates. Technically these are toxins because they are biologically produced and they would be harmful in abnormal concentrations… but they are normal products of biology, and so most of them are either safely excreted, or actually re-used and re-cycled. As in the rest of nature, not much in cellular chemistry is wasted. Lactic acid is the ultimate example: misunderstood for decades, even by many people who should know better, lactic acid isn’t a persistent waste product and you wouldn’t want to “flush” it or “suck” it out of your muscles even if you could.

Read more in any of these articles:

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