This got a mention in a post last week, but it needs a little more direct attention: a new JAMA trial has shown that regular pain-killers work just as well as opioids for severe, acute pain. Amazing.
Maybe we all need to stop thinking of opioids as “powerful”? They may be as over-rated as placebo. See Opioids for Chronic Aches & Pains for the devil that is (always) in the details.