Two articles on PainSci cite Zhang 2011: 1. Digital Motion X-Ray 2. A Rational Guide to Fibromyalgia
PainSci notes on Zhang 2011:
This study demonstrates that much more information can be obtained by imaging the neck in a range of positions (dynamic MRI), as opposed to just a neutral position. 50 patients on their way to neck surgery to help with spinal cord trouble were much more thoroughly scanned than they normally would have been. Cord impingement was spotted in just 17 patients in the neutral position, but thirty-seven in extension (and several in flexion as well). Cord inflammation was visible in just 13 patients in neutral position but twenty in a flexed position. The authors concluded that “Dynamic MRI is useful to determine more accurately the number of levels where the spinal cord is compromised.”
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
STUDY DESIGN: The authors evaluated preoperative modifications of the cervical spinal canal in flexion and extension in 50 patients with cervical spondylotic myelopathy (CSM) and looked for impingement of the spinal cord not diagnosed in the neutral position.
OBJECTIVE: To evaluate the usefulness of preoperative flexion-extension magnetic resonance imaging (MRI) for patients with CSM.
SUMMARY OF BACKGROUND DATA: Dynamic factors contribute to CSM. Although the clinical manifestations and spinal or spinal cord morphology in patients with myelopathy have been reported, to our knowledge, there are no studies that include the cervical spinal cord length, sagittal diameter, and available space in patients with CSM in flexion, extension, and the neutral position.
METHODS: Dynamic MRI changes in canal stenosis during flexion-extension were evaluated in 50 patients with CSM in the supine position. The authors determined length of the cervical cord (LCC, C1-C7), cervical cord sagittal diameter (CCSD, C3-T1), cervical cord available space (CCAS, C3-T1), intramedullary high-intensity signal (IHIS) changes, number of stenosis, and severity of cord impingement in flexion, extension, and the neutral positions.
RESULTS: On both the anterior and posterior edges of the cord, mean LCC in flexion was longer than in extension or the neutral position and longer in the neutral position than in extension (P < 0.05). In all three positions, the average length of the anterior edge of the cervical cord was longer than the posterior edge (P < 0.05). The mean value of CCSD at each level in extension was greater than in flexion or the neutral position (P < 0.05). In the neutral position, CCSDs were greater than in flexion from C4 to C7 (P < 0.05), but this difference failed to reach significance at levels C3 and T1. In the neutral position, CCAS was greater than in either extension or flexion (P < 0.05), and CCAS was greater in flexion than in extension (P < 0.05) at all levels except C6, at which CCAS was greater in flexion than in either extension or the neutral position (P < 0.05). MRI demonstrated functional cord impingement (grade 3 of Mühle) in 6 of the 50 (12%) patients in flexion, in 17 patients (34%) in the neutral position, and in 37 patients (74%) in extension. IHIS was observed in flexion in 20 patients (40%), in the neutral position in 13 patients (26%), and in extension in 7 patients (14%).
CONCLUSION: Cervical spondylotic myelopathy results from the synergistic action of static and dynamic factors, the latter of which play an important role. In some patients, IHIS on T2 images is only visible with the neck in flexion. That might explain why IHIS is first detected after surgery in some patients in whom MRI was obtained before surgery only in the neutral position. Dynamic MRI is useful to determine more accurately the number of levels where the spinal cord is compromised, and to better evaluate narrowing of the canal and IHIS. New information provided by flexion-extension MRI might change our strategy for CSM management.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- Photobiomodulation therapy is not better than placebo in patients with chronic nonspecific low back pain: a randomised placebo-controlled trial. Guimarães 2021 Pain.
- No effect of creatine monohydrate supplementation on inflammatory and cartilage degradation biomarkers in individuals with knee osteoarthritis. Cornish 2018 Nutr Res.
- The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain. Bebee 2021 Med J Aust.
- Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects. Gerhart 2017 Ann Behav Med.
- Modulation in the elastic properties of gastrocnemius muscle heads in individuals with plantar fasciitis and its relationship with pain. Zhou 2020 Sci Rep.