Four articles on PainSci cite Semark 1999: 1. The Complete Guide to IT Band Syndrome 2. Complete Guide to Plantar Fasciitis 3. Post-Exercise, Delayed-Onset Muscle Soreness 4. Repetitive Strain Injuries Tutorial
PainSci summary of Semark 1999: ?This page is one of thousands in the PainScience.com bibliography. It is not a general article: it is focused on a single scientific paper, and it may provide only just enough context for the summary to make sense. Links to other papers and more general information are provided wherever possible.
Experimenters tortured sprinters’ muscles with a savage workout, and the painful results were identical with or without an anti-inflammatory medication. “In conclusion,” they wrote, “the aetiology of the DOMS induced in the trained subjects in this study seems to be independent of inflammatory processes … .”
~ Paul Ingraham
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
The aim of this study was to examine the effects of a prophylactic dose of a local, transcutaneously administered, non-steroidal anti-inflammatory drug on muscle soreness, muscle damage and sprinting performance in young trained males. Twenty-five subjects aged 19+/-3 years, actively participating in rugby union and field hockey, were familiarized with the test procedure and then divided at random into an experimental group (n = 13) and a control group (n = 12). The experimental group received two patches, each containing 40 mg flurbiprofen (TransAct LAT), 12 h before an exercise bout designed to produce delayed-onset soreness (DOMS). The control group received identical non-medicated placebo patches at the same time. Delayed-onset muscle soreness was induced by an exercise protocol consisting of drop jumps (seven sets of 10 repetitions). Serum creatine kinase activity, muscle soreness, muscle girth and acceleration in a maximal sprint over 30 m were measured before the induction of DOMS and at 12, 24, 48 and 72 h thereafter. Plasma lactate concentration was measured 3 min after the 30-m sprint tests. Subjects in both groups had significantly more pain at 24 and 48 h compared with at 12 and 72 h (P < 0.05; Friedman two-way analysis of variance). Thigh girth and serum creatine kinase did not change throughout the experiment. Although plasma lactate concentrations were elevated after the 30-m sprint, there were no differences between groups or as a result of DOMS. The greatest acceleration occurred between 5 and 10 m. This was not affected by the anti-inflammatory drug or DOMS. In conclusion, the aetiology of the DOMS induced in the trained subjects in this study seems to be independent of inflammatory processes or, more specifically, of increases in prostaglandin synthesis in the muscles.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects. Gerhart 2017 Ann Behav Med.
- Modulation in the elastic properties of gastrocnemius muscle heads in individuals with plantar fasciitis and its relationship with pain. Zhou 2020 Sci Rep.
- Association Between Plantar Fasciitis and Isolated Gastrocnemius Tightness. Nakale 2018 Foot Ankle Int.
- A Bayesian model-averaged meta-analysis of the power pose effect with informed and default priors: the case of felt power. Gronau 2017 Comprehensive Results in Social Psychology.
- The neck and headaches. Bogduk 2014 Neurol Clin.