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Autologous growth factor injections in chronic tendinopathy

PainSci » bibliography » Sandrey 2014
Tags: injections, tendinosis, plantar fasciitis, medicine, treatment, pain problems, overuse injury, injury, foot, leg, limbs

Two articles on PainSci cite Sandrey 2014: 1. Tennis Elbow Guide2. Does Platelet-Rich Plasma Injection Work?

original abstract Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.

CONCLUSIONS: Strong evidence indicates that autologous growth factor injections do not improve plantar fasciopathy pain or function when combined with anesthetic agents or when compared with corticosteroid injections, dry needling, or exercise therapy treatments. Furthermore, limited evidence suggests that PRP injections are beneficial. Except for 2 high-quality RCT studies, the rest were methodologically flawed. Additional studies should be conducted using proper control groups, randomization, blinding, and validated disability outcome measures for pain and function. Until then, the results remain speculative because autologous whole-blood and PRP injection treatments are not standardized.

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