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Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases

PainSci » bibliography » Pedersen et al 2015
Tags: exercise, random, good news, self-treatment, treatment

Two articles on PainSci cite Pedersen 2015: 1. Anxiety & Chronic Pain2. Vulnerability to Chronic Pain

PainSci commentary on Pedersen 2015: ?This page is one of thousands in the bibliography. It is not a general article: it is focused on a single scientific paper, and it may provide only just enough context for the summary to make sense. Links to other papers and more general information are provided wherever possible.

This is s a roundup of evidence and prescription guidelines for prescribing exercise for many (26!) different diseases, which is not to say that the science is necessarily complete and perfect. Consider the nuance in Schuch, which found good overall evidence that exercise protects people from “anxiety,” but — despite a huge sample size — could only actually report statistically significant results for a couple specific types (PTSD and agoraphobia). So does exercise work for anxiety? Likely, but “it’s complicated,” as always.

Still, it’s hard not to be impressed by the sheer volume and diversity of the evidence inspiring these authors.

~ Paul Ingraham

original abstract Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.

This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis); metabolic diseases (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type 2 diabetes, type 1 diabetes); cardiovascular diseases (hypertension, coronary heart disease, heart failure, cerebral apoplexy, and claudication intermittent); pulmonary diseases (chronic obstructive pulmonary disease, asthma, cystic fibrosis); musculo-skeletal disorders (osteoarthritis, osteoporosis, back pain, rheumatoid arthritis); and cancer. The effect of exercise therapy on disease pathogenesis and symptoms are given and the possible mechanisms of action are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and dose for prescription of exercise.

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This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights: