PainScience.com • Good advice for aches, pains & injuries

Statin-Associated Autoimmune Myopathy

updated

Tags: medications, muscle, random, harms, self-treatment, treatment, pain problems

Two articles on PainSci cite Mammen 2016: (1) The Complete Guide to Trigger Points & Myofascial Pain(2) 34 Surprising Causes of Pain

PainSci notes on Mammen 2016:

A good review of the phenomenon of muscle pain caused by statins, the popular and important drugs we take to lower cholesterol. For more information, see Dr. Harriet Hall’s reporting on the paper, or my summary of the issue in 34 Surprising Causes of Pain.

original abstract Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.

Statins are widely used and lower the risk of death from cardiovascular causes. In a fraction of patients, an autoimmune myopathy may develop, characterized by the development of autoantibodies to the target enzyme, HMG-CoA reductase.

related content

Specifically regarding Mammen 2016:

This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights: