Two articles on PainSci cite Robergs 2012: 1. Does Massage Therapy Work? 2. A Deep Dive into Delayed-Onset Muscle Soreness
PainSci commentary on Robergs 2012: ?This page is one of thousands in the PainScience.com bibliography. It is not a general article: it is focused on a single scientific paper, and it may provide only just enough context for the summary to make sense. Links to other papers and more general information are provided wherever possible.
Concise, clear summary of the lactic acid myth, by a physiologist, in a journal. This is the single best professional source citation I know of on this topic.
~ Paul Ingraham
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
There is no ‘evil' to muscle lactate production. As there is no clear evidence that lactate has any direct negative effect on muscle contraction, there is also no ‘conundrum' to muscle lactate. Muscle lactate production is essential to sustained, repeated intense muscle contraction. Post-training increases in MCT1 and MCT4 support greater rates and total capacities of muscle lactate efflux during intense exercise performance, thereby allowing for a greater capacity for muscle lactate production and related glycolytic ATP turnover. It is long overdue, based on all aspects of the scientific method, to recognize muscle lactate production as a benefit to intense exercise performance and muscle biochemistry. I encourage researchers and educators alike to present an interpretation of muscle lactate production where the evidence-based view of the benefits of lactate production are espoused rather than a traditional blame of fatigue and acidosis simply because that is how it has always been.
- “From Time Magazine to NBC Commentators: Why is everyone still so confused about lactate (and exercise physiology)?,” Matthew L Goodwin, LetsRun.com.
- “Lactic Acid Is Not Muscles' Foe, It's Fuel,” Gina Kolata, NYTimes.com.
- “Nothing ‘evil' and no ‘conundrum' about muscle lactate production,” Robert Robergs, Experimental Physiology, 2012.
- “Biochemistry of exercise-induced metabolic acidosis,” Robert A Robergs, Farzenah Ghiasvand, and Daryl Parker, American Journal of Physiology, 2004.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- No long-term effects after a three-week open-label placebo treatment for chronic low back pain: a three-year follow-up of a randomized controlled trial. Kleine-Borgmann 2022 Pain.
- Exercise and education versus saline injections for knee osteoarthritis: a randomised controlled equivalence trial. Bandak 2022 Ann Rheum Dis.
- Association of Lumbar MRI Findings with Current and Future Back Pain in a Population-based Cohort Study. Kasch 2022 Spine (Phila Pa 1976).
- A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Yousef 2013 Anaesthesia.
- Is Neck Posture Subgroup in Late Adolescence a Risk Factor for Persistent Neck Pain in Young Adults? A Prospective Study. Richards 2021 Phys Ther.