Vitamin D deficiency: what a pain it is
Two articles on PainSci cite Holick 2003: 1. The Complete Guide to Trigger Points & Myofascial Pain 2. Vitamin D for Pain
PainSci notes on Holick 2003:
In this editorial for Mayo Clinic Proceedings, Holick explains that “Vitamin D deficiency causes muscle weakness and muscle aches and pains in both children and adults.” In reference to Plotnikoff et al, who studied the relationship between D and pain directly and produced quite dramatic data, “The association between nonspecific musculoskeletal pain and vitamin D deficiency was suspected because of a higher prevalence of these symptoms during winter than summer. The study patients ranged in age from 10 to 65 years, and all had symptoms of vitamin D deficiency. Of the more than 90% of patients who were medically evaluated for persistent musculoskeletal pain 1 year or more before screening, none had been tested previously for vitamin D deficiency.”
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
In the current issue of the Mayo Clinic Proceedings, Plotnikoff and Quigley report that 100% of African Americans, East Africans, Hispanics, and American Indians in their Minnesota-based study had deficient levels of vitamin D; overall, 93% of the 150 children and adults in the study, which included broad categories of ethnic groups, were vitamin D–deficient. Is this unexpected? No. Is this newsworthy? Yes.
- “Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain,” Plotnikoff et al, Mayo Clinic Proceedings, 2003.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- Inciting events associated with lumbar disc herniation. Suri 2010 Spine J.
- Prediction of an extruded fragment in lumbar disc patients from clinical presentations. Pople 1994 Spine (Phila Pa 1976).
- Characteristics of patients with low back and leg pain seeking treatment in primary care: baseline results from the ATLAS cohort study. Konstantinou 2015 BMC Musculoskelet Disord.
- Effectiveness and cost-effectiveness of universal school-based mindfulness training compared with normal school provision in reducing risk of mental health problems and promoting well-being in adolescence: the MYRIAD cluster randomised controlled trial. Kuyken 2022 Evid Based Ment Health.
- Is there a relationship between throbbing pain and arterial pulsations? Mirza 2012 J Neurosci.