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Genetics of the sleep-wake cycle and its disorders

PainSci » bibliography » Hamet et al 2006
Tags: sleep, random

One article on PainSci cites Hamet 2006: The Insomnia Guide

PainSci commentary on Hamet 2006: ?This page is one of thousands in the bibliography. It is not a general article: it is focused on a single scientific paper, and it may provide only just enough context for the summary to make sense. Links to other papers and more general information are provided wherever possible.

“Circadian clock genes (Clock, Per) were first isolated in Drosophila, and their homologous counterparts have been found in mammals. Some of the circadian master genes have been shown to influence sleeping behavior. For instance, a point mutation in a human clock gene (Per2) was shown to produce the rare advanced sleep phase syndrome, whereas a functional polymorphism in Per3 is associated with the more frequent delayed sleep phase syndrome.”

~ Paul Ingraham

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