Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
One page on PainSci cites Geneen 2017: A Rational Guide to Fibromyalgia
PainSci notes on Geneen 2017:
Chronic pain, exercise, and physical activity are all heavily studied, and yet the surprising result of this massive review of reviews — a super review of twenty-one other reviews, encompassing 381 studies and more than 37,000 participants — somehow amounts to nothing more than “it’s promising, but more study needed.” How can this be? Because most of those 381 studies were individually small and lame, statistically underpowered. Garbage in, garbage out … on a huge scale.
Where there’s smoke there’s probably at least a small fire: “The available evidence suggests physical activity and exercise is an intervention with few adverse events that may improve pain severity and physical function, and consequent quality of life.” But it’s far from the conclusion we’d like to see (even from underpowered studies). Exercise may be “the closest thing there is to a miracle cure” for many other medical problems, but not so much for chronic pain.
Obvious disclaimer: some kinds of pain are undoubtedly more responsive to exercise than others.
original abstract †Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
related content
- “Exercise for chronic musculoskeletal pain: A biopsychosocial approach,” Booth et al, Musculoskeletal Care, 2017.
- “Reasoning exercise dosage for people with persistent pain,” Lagerman, In Touch, 2018.
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
- Classical Conditioning Fails to Elicit Allodynia in an Experimental Study with Healthy Humans. Madden 2017 Pain Med.
- Topical glyceryl trinitrate (GTN) and eccentric exercises in the treatment of mid-portion achilles tendinopathy (the NEAT trial): a randomised double-blind placebo-controlled trial. Kirwan 2024 Br J Sports Med.
- Placebo analgesia in physical and psychological interventions: Systematic review and meta-analysis of three-armed trials. Hohenschurz-Schmidt 2024 Eur J Pain.
- Recovery trajectories in common musculoskeletal complaints by diagnosis contra prognostic phenotypes. Aasdahl 2021 BMC Musculoskelet Disord.
- Cannabidiol (CBD) products for pain: ineffective, expensive, and with potential harms. Moore 2023 J Pain.