original abstract†Abstracts here may not perfectly match originals, for a variety of technical and practical reasons. Some abstacts are truncated for my purposes here, if they are particularly long-winded and unhelpful. I occasionally add clarifying notes. And I make some minor corrections.
Fundamental to rational, safe, and effective treatment for any orthopaedic condition is an accurate understanding of the etiology of the symptoms. The decades-old paradigm of a pure structural and biomechanical explanation for the genesis of patellofemoral pain is giving way to one in which biologic factors are being given more consideration. It is increasingly evident that a variable mosaic of possible pathophysiologic processes, often caused by simple overload, best accounts for the etiology of patellofemoral pain in most patients. Inflamed synovial lining and fat pad tissues, retinacular neuromas, increased intraosseous pressure, and increased osseous metabolic activity of the patella all have been documented as contributing to the perception of anterior knee pain. Considered together, these processes can be characterized as loss of tissue homeostasis and can be seen as providing a new and alternative explanation for the conundrum of anterior knee pain. Certain high loading conditions of the patellofemoral joint can be of sufficient magnitude to induce the symptomatic loss of tissue homeostasis so that, once initiated, they may persist indefinitely. From this new biologic perspective, it clinically matters little what structural factors may be present in a given joint (such as chondromalacia, patellar tilt or a Q angle above a certain value) if the pain free condition of tissue homeostasis is safely achieved and maintained.
LEVEL OF EVIDENCE: Level V (expert opinion). See the Guidelines for Authors for a complete description of levels of evidence.
These five articles on PainScience.com cite Dye 2005 as a source:
- PS Does Posture Correction Matter? — Posture correction strategies and exercises … and some reasons not to care or bother
- PS Save Yourself from Patellofemoral Pain Syndrome! — Patellofemoral pain syndrome (aka runner’s knee) explained and discussed in great detail, including every imaginable self-treatment option and all the available scientific evidence
- PS Review of Inside Chiropractic: A Patient’s Guide, a book by Samuel Homola — Homola’s book the perfect guide if you like spinal adjustment but you’re wary of chiropractic controversies
- PS Your Back Is Not Out of Alignment — Debunking the obsession with alignment, posture, and other biomechanical bogeymen as major causes of pain
- PS Patellofemoral Pain Diagnosis with Bone Scan — If you have anterior knee pain, should you bother x-ray, MRI, CT scan, or bone scan?
This page is part of the PainScience BIBLIOGRAPHY, which contains plain language summaries of thousands of scientific papers & others sources. It’s like a highly specialized blog. A few highlights:
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- Agreement of self-reported items and clinically assessed nerve root involvement (or sciatica) in a primary care setting. Konstantinou 2012 Eur Spine J.
- Effect of NSAIDs on Recovery From Acute Skeletal Muscle Injury: A Systematic Review and Meta-analysis. Morelli 2017 Am J Sports Med.
- Association of Spinal Manipulative Therapy With Clinical Benefit and Harm for Acute Low Back Pain: Systematic Review and Meta-analysis. Paige 2017 JAMA.