Failure of magnesium sulphate to prevent suxamethonium induced muscle pains
updated
Chestnutt WN, Dundee JW. Failure of magnesium sulphate to prevent suxamethonium induced muscle pains. Anaesthesia. 1985 May;40(5):488–490. PubMed #4014628.
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Muscle pain is one of the side effects of suxamethonium chloride, an anaesthetic drug used to cause short-term paralysis. In this study, injecting magnesium sulphate had no benefit compared to doing nothing, and was “followed by unpleasant side effects.“
original abstract
In fit unpremedicated patients undergoing minor operations and who were ambulant on the afternoon of the operations, pretreatment with magnesium sulphate given intravenously did not reduce the incidence of suxamethonium [anaesthetic] induced myalgia below that in a similar series who received no prophylactic therapy. The injection of magnesium in conscious patients is followed by unpleasant side effects.
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